1: 94 percent / 1 N NaOH / methanol / 4 h 2: 1.) N-methylmorpholin, 1-hydroxybenzotriazole; 2.) N,N'-dicyclohexylcarbodiimide / 1.) CH2Cl2; 2.) CH2Cl2, 1 h, 0 deg C; 24 h at room temp. 3: 1 N NaOH / methanol / 2 h / 40 °C 4: H2 / Pd/10percent on charcoal / methanol / 3 h View Scheme