iron; acetic acid in ethanol 5 h; Heating;

1: 98 percent / triethylamine / CH2Cl2 / 5 h / 20 °C 2: 88 percent / NaOH; K2CO3; tetrabutylammonium hydrogen sulphate / benzene / 12 h / 70 - 80 °C 3: 92 percent / AcOH; Fe dust / ethanol / 5 h / Heating View Scheme

potassium tert-butylate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; palladium diacetate in toluene Buchwald-Hartwig amination; 48 h; Heating;