1-[1-(1H-吲哚-3-基)-3,4-二氢异喹啉-2(1H)-基]乙酮合成路线 （共 3 条）
反应条件
1: 3,4-dihydro-isoquinoline; acetyl chloride in acetonitrile
T=0°C; 0.533333 h;
2: indole With triethylamine in acetonitrile
T=0 - 20°C; 3 h;
参考文献
AMGEN INC.
Patent: WO2009/73203 A1, 2009 ;
Location in patent: Page/Page column 163 ;
WO 2009/073203 A1
反应条件
tert.-butylhydroperoxide; Cu(NO3)2*3H2O in decane
T=0 - 50°C;
参考文献
Ghobrial, Michael; Schnuerch, Michael; Mihovilovic, Marko D.
Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 8781 - 8793
参考文献
Thesing et al.
Chemische Berichte, 1955 , vol. 88, p. 1295,1305
