1: 2,3-dihydro-2-oxo-5-phenyl-1H-pyrrole-4-carboxylic acid ethyl ester With sodium hydride in tetrahydrofuran
T=20°C; 0.5 h;
2: (Z)-N-phenylbenzimidoyl chloride in tetrahydrofuran
T=20°C;
参考文献
Riggs, Richard L.; Morton, Colin J. H.; Slawin, Alexandra M. Z.; Smith, David M.; Westwood, Nicholas J.; Austen, William S. D.; Stuart, Katie E.
Tetrahedron, 2005 , vol. 61, # 47 p. 11230 - 11243
1.1: 100 percent / thionyl chloride / 2 h / 65 °C
2.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C
2.2: 23 percent / tetrahydrofuran / 20 °C
View Scheme
参考文献
Riggs, Richard L.; Morton, Colin J. H.; Slawin, Alexandra M. Z.; Smith, David M.; Westwood, Nicholas J.; Austen, William S. D.; Stuart, Katie E.
Tetrahedron, 2005 , vol. 61, # 47 p. 11230 - 11243
Riggs, Richard L.; Morton, Colin J. H.; Slawin, Alexandra M. Z.; Smith, David M.; Westwood, Nicholas J.; Austen, William S. D.; Stuart, Katie E.
Tetrahedron, 2005 , vol. 61, # 47 p. 11230 - 11243
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C
1.2: 10 percent / tetrahydrofuran / 20 °C
2.1: 63 percent / polyphosphoric acid / 1 h / 120 °C
View Scheme
参考文献
Riggs, Richard L.; Morton, Colin J. H.; Slawin, Alexandra M. Z.; Smith, David M.; Westwood, Nicholas J.; Austen, William S. D.; Stuart, Katie E.
Tetrahedron, 2005 , vol. 61, # 47 p. 11230 - 11243
