7-羟基苯并呋喃-2-羧酸甲酯合成路线 (共 5 条)
反应条件
1: With boron tribromide in dichloromethane
T=-20 - 20°C; Inert atmosphere;
2: With water; sodium hydroxide in dichloromethane
3: With hydrogenchloride in dichloromethane; water
参考文献
Appleton, David R.; Pearce, A. Norrie; Copp, Brent R.
Tetrahedron, 2010 , vol. 66, # 27-28 p. 4977 - 4986
反应条件
hydrogenchloride in methanol
参考文献
Pfizer Inc.
Patent: US4410539 A1, 1983 ;
反应条件
1: aqueous hydrobromic acid; acetic acid
2: hydrogen chloride
View Scheme
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
反应条件
1: ethanol; sodium ethylate / anschliessend Erwaermen mit wss. Kalilauge
2: aqueous hydrobromic acid; acetic acid
3: hydrogen chloride
View Scheme
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826