5-羟基三环[8.2.1.03,8]十三-3,5,7-三烯-13-酮合成路线 （共 7 条）
反应条件
lead(IV) acetate in trifluoroacetic acid
参考文献
Sparey, Tim; Beher, Dirk; Best, Jonathan; Biba, Mirlinda; Castro, Jose L.; Clarke, Earl; Hannam, Joanne; Harrison, Timothy; Lewis, Huw; Madin, Andrew; Shearman, Mark; Sohal, Bindi; Tsou, Nancy; Welch, Christopher; Wrigley, Jonathan
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 19 p. 4212 - 4216
反应条件
hydrogenchloride; lead(IV) tetraacetate; triphenylphosphine in trifluoroacetic acid
参考文献
Merck and Co., Inc.
Patent: US4341904 A1, 1982 ;
反应条件
1: stannous chloride dihydrate, conc. HCl / tetrahydrofuran / 1 h / Ambient temperature
2: 1.) sodium nitrite, sulfuric acid, 2.) H2O, NaSO4 / 1.) water, 0 deg C, 25 min, 2.) sulfuric acid, 50 to 60 deg C
View Scheme
参考文献
Belanger, Patrice C.; Young, Robert N.; Scheigetz John; Dufresne, Claude; Springer, James P.
Journal of Organic Chemistry, 1982 , vol. 47, # 22 p. 4329 - 4334
反应条件
sulfuric acid; water; sodium nitrite
1.) water, 0 deg C, 25 min, 2.) sulfuric acid, 50 to 60 deg C; Yield given. Multistep reaction;
参考文献
Belanger, Patrice C.; Young, Robert N.; Scheigetz John; Dufresne, Claude; Springer, James P.
Journal of Organic Chemistry, 1982 , vol. 47, # 22 p. 4329 - 4334
反应条件
potassium carbonate in acetone
Ambient temperature;
参考文献
Belanger, Patrice C.; Young, Robert N.; Scheigetz John; Dufresne, Claude; Springer, James P.
Journal of Organic Chemistry, 1982 , vol. 47, # 22 p. 4329 - 4334
反应条件
1: 83 percent / potassium carbonate / acetone / Ambient temperature
2: 95 percent / hydroxylamine hydrochloride, pyridine / ethanol / 0.25 h / Heating
3: 97.6 percent / H2 / platinum oxide / acetic acid / 2.5 h / 1034.3 Torr
View Scheme
参考文献
Belanger, Patrice C.; Young, Robert N.; Scheigetz John; Dufresne, Claude; Springer, James P.
Journal of Organic Chemistry, 1982 , vol. 47, # 22 p. 4329 - 4334
反应条件
1: 96 percent / hydroxylamine hydrochloride, pyridine / ethanol / 0.25 h / Heating
2: 94 percent / H2 / platinum oxide / acetic acid / 2.5 h / 1034.3 Torr
View Scheme
参考文献
Belanger, Patrice C.; Young, Robert N.; Scheigetz John; Dufresne, Claude; Springer, James P.
Journal of Organic Chemistry, 1982 , vol. 47, # 22 p. 4329 - 4334
