反应条件
1: 2-bromo-5-(methoxymethyl)thiophene With n-butyllithium in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane T=-78°C; 0.0333333 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane T=20°C;
参考文献
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; PROVID PHARMACEUTICALS INC.; EBRIGHT, Richard H.; EBRIGHT, Yon W.; SHEN, Juan; BACCI, James; HIEBEL, Anne-Cecile; SOLVIBILE, William; SELF, Christopher; OLSON, Gary
Patent: WO2013/192352 A1, 2013 ;
Location in patent: Page/Page column 92; 93 ;