4,5-二氯-3,6-二羟基-2,7-二甲氧基-3-氧代-3H-螺[异苯并呋喃-1,9-氧杂蒽]-5-羧酸合成路线 （共 3 条）
反应条件
1: chlorine / chloroform / 2.5 h
2: selenium(IV) oxide; dihydrogen peroxide / dichloromethane; water / 48 h / 20 °C
3: hydrogenchloride; methanol / 0.5 h / 20 °C
4: methanesulfonic acid; tin(IV) chloride / 6 h / 40 °C
View Scheme
参考文献
Tsybulsky, Dmitry A.; Kvach, Maksim V.; Stepanova, Irina A.; Korshun, Vladimir A.; Shmanai, Vadim V.
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 977 - 984
反应条件
1: selenium(IV) oxide; dihydrogen peroxide / dichloromethane; water / 48 h / 20 °C
2: hydrogenchloride; methanol / 0.5 h / 20 °C
3: methanesulfonic acid; tin(IV) chloride / 6 h / 40 °C
View Scheme
参考文献
Tsybulsky, Dmitry A.; Kvach, Maksim V.; Stepanova, Irina A.; Korshun, Vladimir A.; Shmanai, Vadim V.
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 977 - 984
反应条件
methanesulfonic acid; tin(IV) chloride
T=40°C; 6 h;
参考文献
Tsybulsky, Dmitry A.; Kvach, Maksim V.; Stepanova, Irina A.; Korshun, Vladimir A.; Shmanai, Vadim V.
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 977 - 984
