1,8-二羟基-2,3,4,6-四甲氧基-9H-氧杂蒽-9-酮合成路线 （共 5 条）
反应条件
hydrogen bromide in acetic acid
T=100°C; 0.25 h;
参考文献
Simoneau, Bruno; Brassard, Paul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1507 - 1510
反应条件
1: 88 percent / KF / dimethylformamide / 1 h / 100 - 110 °C
2: 1.) aq. Na2S2O4, 2.) conc. H2SO4 / 1.) CH2Cl2, 2.) 5 min (room temperature), 15 - 20 min, 60 deg C
3: 84 percent / K2CO3 / acetone
4: 46 percent / HBr / acetic acid / 0.25 h / 100 °C
View Scheme
参考文献
Simoneau, Bruno; Brassard, Paul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1507 - 1510
反应条件
1: 88 percent / KF / dimethylformamide / 1 h / 100 - 110 °C
2: 1.) aq. Na2S2O4, 2.) conc. H2SO4 / 1.) CH2Cl2, 2.) 5 min (room temperature), 15 - 20 min, 60 deg C
3: 84 percent / K2CO3 / acetone
4: 46 percent / HBr / acetic acid / 0.25 h / 100 °C
View Scheme
参考文献
Simoneau, Bruno; Brassard, Paul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1507 - 1510
反应条件
1: 84 percent / K2CO3 / acetone
2: 46 percent / HBr / acetic acid / 0.25 h / 100 °C
View Scheme
参考文献
Simoneau, Bruno; Brassard, Paul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1507 - 1510
反应条件
1: 1.) aq. Na2S2O4, 2.) conc. H2SO4 / 1.) CH2Cl2, 2.) 5 min (room temperature), 15 - 20 min, 60 deg C
2: 84 percent / K2CO3 / acetone
3: 46 percent / HBr / acetic acid / 0.25 h / 100 °C
View Scheme
参考文献
Simoneau, Bruno; Brassard, Paul
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1507 - 1510
