6,7-二氢-2-苯基-5H-吡咯[2,1-c]-1,2,4-三唑氯化物合成路线 （共 3 条）
反应条件
1: CH4O4S*C10H13N3 With potassium hydroxide in dichloromethane; water
2: With hydrogenchloride in methanol; water
3: trimethyl orthoformate With hydrogenchloride in methanol; water
Reflux;
参考文献
Ueng, Shau-Hua; Brahmi, Malika Makhlouf; Derat, Etienne; Fensterbank, Louis; Lacote, Emmanuel; Malacria, Max; Curran, Dennis P.
Journal of the American Chemical Society, 2008 , vol. 130, # 31 p. 10082 - 10083
反应条件
hydrogenchloride in 1,2-dichloro-benzene
T=120°C; 12 h;
参考文献
Kerr, Mark S.; Read De Alaniz, Javier; Rovis, Tomislav
Journal of Organic Chemistry, 2005 , vol. 70, # 14 p. 5725 - 5728
反应条件
1: pyrrolidin-2-one; dimethyl sulfate in acetonitrile
T=80°C; 17 h;
2: phenylhydrazine in acetonitrile
T=80°C; 4 h;
3: trimethyl orthoformate Further stages;
参考文献
Kena-diba, Anastasie; Noll, Claudia; Richter, Michael; Gieseler, Marc Timo; Kalesse, Markus
Angewandte Chemie - International Edition, 2010 , vol. 49, # 45 p. 8367 - 8369
