2-苄基-1,1,3,3-四甲基异吲哚啉合成路线 （共 6 条）
反应条件
1: methyl iodide With magnesium in diethyl ether
T=80°C;
2: N-Benzylphthalimide in toluene
T=108 - 110°C;
参考文献
Frantz, Marie-Celine; Skoda, Erin M.; Sacher, Joshua R.; Epperly, Michael W.; Goff, Julie P.; Greenberger, Joel S.; Wipf, Peter
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 25 p. 4147 - 4153
反应条件
in toluene
T=110°C; 4 h;
参考文献
Chan, Kin Shing; Li, Xin Zhu; Lee, Siu Yin
Organometallics, 2010 , vol. 29, # 13 p. 2850 - 2856
反应条件
in toluene
T=200°C; Grignard reaction; P=9000.9 - 15001.5 Torr; 2 h; microwave irradiation;
参考文献
Foitzik, Richard C.; Bottle, Steven E.; White, Jonathan M.; Scammells, Peter J.
Australian Journal of Chemistry, 2008 , vol. 61, # 3 p. 168 - 171
反应条件
1: acetic acid / 1 h / |Reflux
2: toluene / 4 h / |Reflux
View Scheme
参考文献
Thomas, Komba; Chalmers, Benjamin A.; Fairfull-Smith, Kathryn E.; Bottle, Steven E.
European Journal of Organic Chemistry, 2013 , # 5 p. 853 - 857
参考文献
Griffiths, Peter G.; Moad, Graeme; Rizzardo, Ezio; Solomon, David H.
Australian Journal of Chemistry, 1983 , vol. 36, # 2 p. 397 - 401
反应条件
hydrogen; palladium on activated charcoal in acetic acid
参考文献
Griffiths, Peter G.; Moad, Graeme; Rizzardo, Ezio; Solomon, David H.
Australian Journal of Chemistry, 1983 , vol. 36, # 2 p. 397 - 401
