4-羟基-7,8-二甲氧基-5-(苯基甲氧基)-2-萘羧酸乙酯合成路线 （共 8 条）
反应条件
ethanol; potassium carbonate
T=20°C; 18 h;
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 10 p. 1925 - 1930
反应条件
1.1: NaH / tetrahydrofuran / 20 °C
1.2: 77 percent / TFA / H2O / 20 °C
2.1: 92 percent / KOAc / Heating
3.1: K2CO3 / ethanol / 20 °C
View Scheme
参考文献
Shimbashi, Akiko; Ishikawa, Yuichi; Nishiyama, Shigeru
Tetrahedron Letters, 2004 , vol. 45, # 5 p. 939 - 941
反应条件
1: 92 percent / KOAc / Heating
2: K2CO3 / ethanol / 20 °C
View Scheme
参考文献
Shimbashi, Akiko; Ishikawa, Yuichi; Nishiyama, Shigeru
Tetrahedron Letters, 2004 , vol. 45, # 5 p. 939 - 941
反应条件
1: 92 percent / K2CO3 / dimethylformamide / 20 °C
2: 80 percent / LiAlH4 / tetrahydrofuran / 20 °C
3: 100 percent / SO3*Py; DMSO; TEA / CH2Cl2 / 20 °C
4: 100 percent / NaH / dimethylsulfoxide; tetrahydrofuran / 0 °C
View Scheme
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 61 - 65
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 61 - 65
反应条件
1: 92 percent / K2CO3 / dimethylformamide / 20 °C
2: 80 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 61 - 65
反应条件
1: 92 percent / K2CO3 / dimethylformamide / 20 °C
2: 80 percent / LiAlH4 / tetrahydrofuran / 20 °C
3: 100 percent / SO3*Py; DMSO; TEA / CH2Cl2 / 20 °C
View Scheme
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 61 - 65
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=20°C;
参考文献
Shimbashi, Akiko; Tsuchiya, Ayako; Imoto, Masaya; Nishiyama, Shigeru
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 61 - 65
