2,4-二甲氧基苯乙酮合成路线 (共 100 条)
反应条件
potassium hydroxide; ethanol
参考文献
Savkar; Bokil; Nargund
Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1940 , vol. 9/, p. 150,153
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Vandrewalla; Jadhav
Journal of the University of Bombay, Science: Physical Sciences, Mathematics, Biological Sciences and Medicine, 1948 , vol. 16/A, p. 43
反应条件
1: sodium / 125 °C
2: aqueous hydriodic acid / 130 °C
View Scheme
参考文献
Hattori
Acta Phytochimica, 1932 , vol. 6, p. 131,152
反应条件
hydrogenchloride in ethanol
8 h; Heating;
参考文献
Carter, Rachel H.; Garson, Mary J.; Hill, Robert A.; Staunton, James; Sunter, David C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 471 - 479
反应条件
1: With acetic anhydride; copper(II) nitrate
3 h;
2: With ammonia; ammonium chloride in water
T=0°C;
参考文献
Piotrowski, David W.; Rogers, Bruce N.; McWhorter JR., William W.; Walker, Daniel Patrick; Corbett, Jeffrey W.; Groppi JR., Vincent E.; Rudmann, Daniel G.
Patent: US2003/236287 A1, 2003 ;
Location in patent: Page 32 ;
US 20030236287 A1
反应条件
tetrabutyl-ammonium chloride; 3,3-dimethyldioxirane in acetone
T=0°C; regioselective reaction;
参考文献
Lee, Yean-Jang; Wu, Huan-Ting; Lin, Chia-Ning
Letters in Organic Chemistry, 2009 , vol. 6, # 7 p. 585 - 587
反应条件
sodium hydroxide in methanol
T=28°C; Claisen Schmidt condensation;
参考文献
Liu; Wilairat; Go
Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4443 - 4452
反应条件
1: AlCl3; benzene / 100 - 110 °C
2: aqueous acetic acid; bromine
View Scheme
参考文献
Shinoda; Sato; Kawagoye
Yakugaku Zasshi, 1932 , vol. 52, p. 766,773;dtsch.Ref.S.91
Chem.Abstr., 1933 , p. 295
反应条件
1: OH- / ethanol
2: 1.9 g / H2O2, OH-
View Scheme
参考文献
Bezuidenhoudt, Barend C. B.; Brandt, E. Vincent; Roux, David G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 263 - 269
反应条件
1: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Davies et al.
Journal of the Chemical Society, 1957 , p. 3154,3156
反应条件
perchloric acid; thallium(III) nitrate
T=20°C; Oxidation; 1 h;
参考文献
Alesso, E. N.; Aguirre, J. M.; Iglesias, G. Y. Moltrasio
Organic Preparations and Procedures International, 1992 , vol. 24, # 6 p. 690 - 692