2,4-二甲氧基苯乙酮合成路线 （共 100 条）
反应条件
1: I2, CF3CO2Ag / CHCl3 / Ambient temperature
2: 90 percent / PPh3, Et3N, PdCl2, CuI / dimethylformamide / 0.5 h / 85 °C
3: H2 / Raney Ni / methanol / 20 °C
4: 81 percent / TsOH*H2O / toluene / Heating
View Scheme
参考文献
Tsukayama, Masao; Kikuchi, Makoto; Kawamura, Yasuhiko
Heterocycles, 1994 , vol. 38, # 7 p. 1487 - 1490
反应条件
bis-(pentafluoro phenyl) dibromo stannane in dichloromethane
T=-78°C; parallel recognition; 5 h;
参考文献
Chen, Jian-Xie; Sakamoto, Katsumasa; Orita, Akihiro; Otera, Junzo
Tetrahedron, 1998 , vol. 54, # 29 p. 8411 - 8420
反应条件
1: copper(ll) bromide / ethyl acetate; chloroform / 10 h / |Inert atmosphere; |Reflux
2: sodium chloride / water / 168 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Al-Rifai, Nafisah; Ruecker, Hannelore; Amslinger, Sabine
Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15384 - 15395
反应条件
1: sulfur / 6 h / 130 °C
2: sodium hydroxide / water / 3 h / 100 - 102 °C
3: triethylamine
4: pyridine hydrochloride
View Scheme
参考文献
Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421
反应条件
1: sulfur / 6 h / 130 °C
2: sodium hydroxide / water / 3 h / 100 - 102 °C
3: triethylamine
View Scheme
参考文献
Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421
反应条件
1: sulfur / 6 h / 130 °C
2: sodium hydroxide / water / 3 h / 100 - 102 °C
3: triethylamine
4: pyridine hydrochloride
5: pyridine
View Scheme
参考文献
Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421
反应条件
1: sulfur / 6 h / 130 °C
2: sodium hydroxide / water / 3 h / 100 - 102 °C
3: triethylamine
4: pyridine hydrochloride
5: pyridine
6: N-bromosuccinmide; benzoic acid anhydride; tetrachloromethane
View Scheme
参考文献
Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421
反应条件
1: sulfur / 6 h / 130 °C
2: sodium hydroxide / water / 3 h / 100 - 102 °C
3: triethylamine
4: potassium carbonate / methanol
5: potassium carbonate / N,N-dimethyl-formamide
View Scheme
参考文献
Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421
反应条件
titanium(III) chloride; lithium in tetrahydrofuran
参考文献
Banerji, Asoke; Nayak, Sandip, K.
Journal of the Chemical Society, Chemical Communications, 1991 , # 20 p. 1432 - 1434
反应条件
sodium hydride in toluene; paraffin oil
2 h; Inert atmosphereReflux;
参考文献
Al-Rifai, Nafisah; Ruecker, Hannelore; Amslinger, Sabine
Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15384 - 15395
