9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
sodium hydrogencarbonate in tetrahydrofuran 2 h;
参考文献
Kahnberg, Pia; Lucke, Andrew J.; Glenn, Matthew P.; Boyle, Glen M.; Tyndall, Joel D. A.; Parsons, Peter G.; Fairlie, David P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7611 - 7622
反应条件
triethylamine in water; acetonitrile T=20°C; pH=8.5 - 9.0; 0.5 h;
参考文献
Herzner, Holger; Kunz, Horst
Tetrahedron, 2007 , vol. 63, # 28 p. 6423 - 6436
反应条件
1: 98 percent / sodium carbonate / dioxane; H2O / 0 - 20 °C 2: 83 percent / triphenylphosphine; N-bromo-succinimide / tetrahydrofuran / 0 - 20 °C 3: 100 percent / sodium sulfite; H2O / dioxane / 1 h / 100 °C 4: 76 percent / subtilisin; aq. NaOH / aq. phosphate buffer / 4 h / 20 °C View Scheme
参考文献
Herzner, Holger; Kunz, Horst
Tetrahedron, 2007 , vol. 63, # 28 p. 6423 - 6436
反应条件
sodium sulfate in 1,4-dioxane; water 1.) 0 deg C, 3 h; 2.) 20 deg C, 16 h;
参考文献
Synthesis, , # 3 p. 265 - 270
反应条件
1.1: 78 percent / aq. NaHCO3 / acetone / 48 h / 20 °C 2.1: 84 percent / H2SO4 / CH2Cl2 / 19 h / 20 °C 3.1: 99 percent / NaI / acetone / 72 h / Heating 4.1: Zn; Me3SiCl / dimethylformamide / 20 °C 4.2: 34 percent / P(o-tol)3 / tris(dibenzylideneacetone)dipalladium / dimethylformamide / 4 h / 50 °C 5.1: 64 percent / Et3SiH; TFA / CH2Cl2 / 4 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
反应条件
sodium hydrogencarbonate
参考文献
European Journal of Organic Chemistry, , # 20-21 p. 3685 - 3689
反应条件
1: CH2Cl2 / 70 h / Ambient temperature 2: MeOH / CH2Cl2 / 0.5 h / Ambient temperature View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 30, # 2 p. 183 - 186
反应条件
1: anhydrous L-asparagine With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
sodium carbonate in tetrahydrofuran; water
参考文献
US2006/161007 A1, ;
Page/Page column 12 ;
反应条件
sodium hydroxide; anhydrous potassium hydrogen sulfate; carbon dioxide in 1,4-dioxane; water
参考文献
Hoechst Aktiengesellschaft
Patent: US6121418 A1, 2000 ;
