9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
triethylamine in tetrahydrofuran; water; acetonitrile T=20°C; pH=8.5; 3 h;
参考文献
Tevyashova; Olsufyeva; Preobrazhenskaya; Klyosov; Zomer; Platt
Russian Journal of Bioorganic Chemistry, 2007 , vol. 33, # 1 p. 139 - 145
反应条件
TEA in water; N,N-dimethyl-formamide 1 h;
参考文献
Fujii; Futaki; Funakoshi; Akaji; Morimoto; Doi; Inoue; Kogire; Sumi; Yun; Tobe; Aono; Matsuda; Narusawa; Moriga; Yajima
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 9 p. 3281 - 3291
反应条件
sodium hydroxide 1.) H2O, 0 deg C, 2 h; 2.) p-dioxane, 0 deg C to r.t., 24 h; Yield given. Multistep reaction;
参考文献
Adamson, J. Gordon; Blaskovich, Mark A.; Groenevelt, Hester; Lajoie, Gilles A.
Journal of Organic Chemistry, 1991 , vol. 56, # 10 p. 3447 - 3449
反应条件
1: H-tyrosine(t-Bu)-OH With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
1: 97 percent / 10percent Na2CO3 / dioxane; H2O / 20 h / 0 deg C to r.t. 2: 83 percent / conc. H2SO4 / CH2Cl2 / 6 h / 258.6 Torr / Ambient temperature 3: 74 percent / aq. Na2CO3 / acetonitrile / 15 h View Scheme
参考文献
Adamson, J. Gordon; Blaskovich, Mark A.; Groenevelt, Hester; Lajoie, Gilles A.
Journal of Organic Chemistry, 1991 , vol. 56, # 10 p. 3447 - 3449
反应条件
sodium carbonate 1.) H2O, r.t., 24 h; 2.) p-dioxane, 0 deg C to r.t., 24 h; other reagent (1. step): NaOH; Yield given. Multistep reaction;
参考文献
Adamson, J. Gordon; Blaskovich, Mark A.; Groenevelt, Hester; Lajoie, Gilles A.
Journal of Organic Chemistry, 1991 , vol. 56, # 10 p. 3447 - 3449
参考文献
Wang, Jidong; Okada, Yoshio; Li, Wei; Yokoi, Toshio; Zhu, Jintao
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 5 p. 621 - 624
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water T=0 - 20°C;
参考文献
Pandey, Anil K.; Naduthambi, Devan; Thomas, Krista M.; Zondlo, Neal J.
Journal of the American Chemical Society, 2013 , vol. 135, # 11 p. 4333 - 4363
反应条件
in tetrahydrofuran T=20°C; 24 h;
参考文献
Miyawaki, Atsuhisa; Miyauchi, Masahiko; Takashima, Yoshinori; Yamaguchi, Hiroyasu; Harada, Akira
Chemical Communications, 2008 , vol. 8, # 4 p. 456 - 458
反应条件
sodium carbonate in tetrahydrofuran T=20°C; 2 h;
参考文献
Zanardi, Franca; Burreddu, Paola; Rassu, Gloria; Auzzas, Luciana; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Nicastro, Giuseppe; Menchi, Gloria; Cini, Nicoletta; Bottonocetti, Anna; Raspanti, Silvia; Casiraghi, Giovanni
Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1771 - 1782
