9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
potassium carbonate in water; acetonitrile T=20°C; 0.5 h; Product distribution / selectivity;
参考文献
Medarex, Inc.
Patent: US2010/145036 A1, 2010 ;
Location in patent: Page/Page column 87 ;
反应条件
in 1,4-dioxane; water T=20°C; 16 h;
参考文献
Crestey, Francois; Ottesen, Lars K.; Jaroszewski, Jerzy W.; Franzyk, Henrik
Tetrahedron Letters, 2008 , vol. 49, # 41 p. 5890 - 5893
反应条件
1: N(im)-trityl-L-histidine With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
sodium hydrogencarbonate in water; acetone T=20°C;
参考文献
Gu, Xuyuan; Ying, Jinfa; Agnes, Richard S.; Navratilova, Edita; Davis, Peg; Stahl, Gannon; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J.
Organic Letters, 2004 , vol. 6, # 19 p. 3285 - 3288
反应条件
triethylamine in water; acetonitrile 0.5 h; pH=8.5-9.0;
参考文献
Sakina; Kawazura; Morihara; Yajima
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 10 p. 3915 - 3919
反应条件
triethylamine in water; acetonitrile 0.5 h; pH=8.5-9.0;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 36, # 10 p. 3915 - 3919
反应条件
sodium carbonate in 1,4-dioxane; water T=0°C; 2 h; Inert atmosphereSchlenk technique;
参考文献
Pfeiffer, Hendrik; Sowik, Thomas; Schatzschneider, Ulrich
Journal of Organometallic Chemistry, 2013 , vol. 734, p. 17 - 24
反应条件
sodium carbonate in 1,4-dioxane; water Ambient temperature;
参考文献
Booth, Susan; Wallace, Emma N. K.; Singhal, Kavita; Bartlett, Philip N.; Kilburn, Jeremy D.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 9 p. 1467 - 1474
反应条件
sodium hydroxide in 1,4-dioxane pH 9;
参考文献
Theobald, Paula; Porter, John; Rivier, Catherine; Corrigan, Anne; Hook, William; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2395 - 2402
反应条件
in sodium hydroxide T=0 - 20°C; 22 h;
参考文献
McElroy, Andrew B.; Clegg, Stephen P.; Deal, Martyn J.; Ewan, Georg B.; Hagan, Russell M.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2582 - 2591
