9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 (共 303 条)
反应条件
sodium carbonate in tetrahydrofuran; water 3 h;
参考文献
Lyttle; Hocker; Hui; Caldwell; Aaron; Engqvist- Goldstein; Flatgaard; Bauer
Journal of Medicinal Chemistry, 1994 , vol. 37, # 1 p. 189 - 194
反应条件
sodium carbonate in 1,4-dioxane T=20°C;
参考文献
Song, Yan-Li; Peach, Megan L.; Roller, Peter P.; Qiu, Su; Wang, Shaomeng; Long, Ya-Qiu
Journal of Medicinal Chemistry, 2006 , vol. 49, # 5 p. 1585 - 1596
反应条件
potassium carbonate in 1,4-dioxane; water 3 h;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
potassium carbonate in 1,4-dioxane; water 3 h;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
hydrogenchloride; TEA; water in acetonitrile 0.5 h; Yield given;
参考文献
Kruijtzer, John A.W.; Hofmeyer, Lovina J.F.; Heerma, Wigger; Versluis, Cornelis; Liskamp, Rob M.J.
Chemistry - A European Journal, 1998 , vol. 4, # 8 p. 1570 - 1580
反应条件
in water; acetonitrile T=20°C; 0.5 h;
参考文献
Jahnsen, Rasmus D.; Frimodt-Moller, Niels; Franzyk, Henrik
Journal of Medicinal Chemistry, 2012 , vol. 55, # 16 p. 7253 - 7261
反应条件
1: (S)-2-amino-5-(allyloxy)-5-oxopentanoic acid hydrochloride With potassium carbonate in water T=0°C; 0.333333 h; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione in 1,4-dioxane; water T=20°C; 8 h; Further stages.;
参考文献
Mittapalli, Gopi Kumar; Osornio, Yazmin M.; Guerrero, Miguel A.; Reddy, Kondreddi Ravinder; Krishnamurthy, Ramanarayanan; Eschenmoser, Albert
Angewandte Chemie - International Edition, 2007 , vol. 46, # 14 p. 2478 - 2484
参考文献
Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water T=20°C; Acylation; 2 h;
参考文献
Yu, Chongxi; Taylor, John W.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 1 p. 161 - 175
反应条件
1: 94 percent / CuSO4, NaOH / H2O / 72 h / Ambient temperature 2: 50 percent / aq. Na2CO3 / dioxane / 1.) 0 deg C, 1 h; 2.) r.t., 22 h View Scheme
参考文献
Galpin; Mohammed; Patel
Tetrahedron, 1988 , vol. 44, # 6 p. 1773 - 1782