9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 (共 303 条)
反应条件
sodium hydroxide in 1,4-dioxane; methanol T=25°C; 4 h; Yield given;
参考文献
Sharma, Sushil K.; Songster, Michael F.; Colpitts, Tracey L.; Hegyes, Peter; Barany, George; Castellino, Francis J.
Journal of Organic Chemistry, 1993 , vol. 58, # 18 p. 4993 - 4996
反应条件
sodium carbonate in 1,4-dioxane T=25°C; 3 h;
参考文献
Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany
Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
反应条件
sodium hydroxide 1.) dioxane, 1.5h; Multistep reaction;
参考文献
Albericio; Kneib-Cordonier; Biancalana; Gera; Masada; Hudson; Barany
Journal of Organic Chemistry, 1990 , vol. 55, # 12 p. 3730 - 3743
反应条件
sodium carbonate in 1,4-dioxane; water T=20°C; 16 h;
参考文献
Chemistry - An Asian Journal, , vol. 6, # 6 p. 1316 - 1320
反应条件
potassium carbonate in water 16 h;
参考文献
Organic Letters, , vol. 7, # 9 p. 1699 - 1702
反应条件
sodium hydrogencarbonate in tetrahydrofuran; water T=0 - 20°C;
参考文献
CHOONGWAE PHARMA CORPORATION
Patent: WO2004/108731 A1, 2004 ;
Location in patent: Page 73 ;
反应条件
1: (S)-2-phenylglycine With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
sodium hydroxide in 1,4-dioxane; water T=20°C; pH=8 - 9; 2.5 h;
参考文献
Isaad, Alexandra Le Chevalier; Barbetti, Francesca; Rovero, Paolo; D'Ursi, Anna Maria; Chelli, Mario; Chorev, Michael; Papini, Anna Maria
European Journal of Organic Chemistry, 2008 , # 31 p. 5308 - 5314
反应条件
sodium carbonate in N,N-dimethyl-formamide T=0 - 20°C; Substitution;
参考文献
Gopalakrishnan, Ranganath; Kozany, Christian; Gaali, Steffen; Kress, Christoph; Hoogeland, Bastiaan; Bracher, Andreas; Hausch, Felix
Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4114 - 4122
反应条件
Alkaline conditions;
参考文献
Sleebs, Marianne M.; Scanlon, Denis; Karas, John; Maharani, Rani; Hughes, Andrew B.
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6686 - 6693