9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
sodium carbonate in water; N,N-dimethyl-formamide 0.25 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 11 p. 1335 - 1340
反应条件
1: trans-4-aminomethyl-cyclohexane-1-carboxylic acid With triethylamine in water T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione in water; acetonitrile T=20°C;
参考文献
Dener, Jeffrey M.; Fantauzzi, Pascal P.; Kshirsagar, Tushar A.; Kelly, Daphne E.; Wolfe, Aaron B.
Organic Process Research and Development, 2001 , vol. 5, # 4 p. 445 - 449
反应条件
sodium carbonate in 1,4-dioxane; water T=20°C; 2 h;
参考文献
Gessier, Francois; Schaeffer, Laurent; Kimmerlin, Thierry; Floegel, Oliver; Seebach, Dieter
Helvetica Chimica Acta, 2005 , vol. 88, # 8 p. 2235 - 2249
反应条件
1: 5.41 g / N-methylmorpholine / CH2Cl2 / 6 h / 20 °C 2: 89.8 percent / acetic acid; zinc / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 42 p. 8453 - 8459
反应条件
triethylamine in methanol Yield given;
参考文献
Tetrahedron Letters, , vol. 39, # 10 p. 1169 - 1172
反应条件
1: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 2: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
sodium carbonate in tetrahydrofuran T=20°C; 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 6 p. 1771 - 1782
反应条件
sodium hydrogencarbonate in acetone Ambient temperature;
参考文献
Djedaini-Pilard, Florence; Azaroual-Bellanger, Nathalie; Gosnat, Muriel; Vernet, Delphine; Perly, Bruno
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 4 p. 723 - 730
反应条件
1: CH2Cl2 / 24 h / Ambient temperature 2: MeOH / CH2Cl2 / 0.5 h / Ambient temperature View Scheme
参考文献
Raillard, Stephen P.; Mann, Adam D.; Baer, Ted A.
Organic Preparations and Procedures International, 1998 , vol. 30, # 2 p. 183 - 186
反应条件
1: With sodium hydrogencarbonate in tetrahydrofuran T=20°C; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
Myriad Pharmaceuticals, Inc.
Patent: US2004/14763 A1, 2004 ;
Location in patent: Page 23 ;
