9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
1: 83 percent / NaOH / dioxane; H2O / 40 °C / pH 8 - 9 2: 98 percent / TFA / CH2Cl2 / 1.5 h / 20 °C View Scheme
参考文献
Papini, Anna Maria; Nardi, Elena; Nuti, Francesca; Uziel, Jacques; Ginanneschi, Mauro; Chelli, Mario; Brandi, Alberto
European Journal of Organic Chemistry, 2002 , # 16 p. 2736 - 2741
反应条件
sodium carbonate in 1,4-dioxane T=0°C; 24 h;
参考文献
Schmidt, Boris; Patzke, Greta R.
Synthetic Communications, 1999 , vol. 29, # 6 p. 1025 - 1032
反应条件
1: ethyl N-(2-propenyl)glycinate With sodium hydroxide in 1,4-dioxane; methanol; water Hydrolysis; 0.75 h; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium hydroxide in 1,4-dioxane; methanol; water Acylation; pH=8.5 - 9.0; 16 h; Further stages.;
参考文献
Reichwein, John F.; Liskamp, Rob M. J.
European Journal of Organic Chemistry, 2000 , # 12 p. 2335 - 2344
反应条件
1: N-allylglycine methyl ester With water; sodium hydroxide T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium hydrogencarbonate in 1,4-dioxane; water T=20°C;
参考文献
Liu, Fa; Stephen, Andrew G.; Waheed, Abdul A.; Freed, Eric O.; Fisher, Robert J.; Burke Jr., Terrence R.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 318 - 321
反应条件
sodium carbonate in acetone 2 h;
参考文献
Abele, Stefan; Guichard, Gilles; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 12 p. 2141 - 2156
反应条件
Ba(ClO4)2; triethylamine in N,N-dimethyl-formamide T=20°C; Substitution; 2 h;
参考文献
Raydnov, M. G.; Klimenko, L. V.; Mitin, Yu. V.
Russian Journal of Bioorganic Chemistry, 1999 , vol. 25, # 5 p. 283 - 287
Bioorganicheskaya Khimiya, 1999 , vol. 25, # 5 p. 323 - 328
反应条件
sodium hydrogencarbonate in acetone Ambient temperature;
参考文献
Djedaini-Pilard, Florence; Azaroual-Bellanger, Nathalie; Gosnat, Muriel; Vernet, Delphine; Perly, Bruno
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 4 p. 723 - 730
反应条件
sodium carbonate in N,N-dimethyl-formamide 0.166667 h; Ambient temperature;
参考文献
Lapatsanis, Lucas; Milias, George; Froussios, Kleanthis; Kolovos, Miltiadis
Synthesis, 1983 , # 8 p. 671 - 673
反应条件
1: With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 2: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
1: 78 percent / aq. NaHCO3 / acetone / 48 h / 20 °C 2: 84 percent / H2SO4 / CH2Cl2 / 19 h / 20 °C 3: 99 percent / NaI / acetone / 72 h / Heating View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 16 p. 1876 - 1884
