1: tert-butyl alcohol With n-butyllithium in tetrahydrofuran; hexane T=-20°C; 0.25 h; Inert atmosphere; 2: methyl ester of aziridine-2-carboxylic acid in tetrahydrofuran; hexane T=-20°C; Inert atmosphere;

4-methyl-morpholine; sodium hydroxide; O-(diphenyl-phosphinyl)hydroxylamine in acetonitrile T=20°C; 10 h;

ammonia 2 h;

in benzene T=160°C; 12 h;