反应条件
1: dimethylformamide / 80 h / 110 °C 2: 243.3 g / aq. hydrazine hydrate / tetrahydrofuran; methanol / 10 - 20 °C 3: 72.2 percent / acetic acid / 5 - 20 °C 4: 87.3 percent / dimethylformamide; H2O / 6 h / Heating 5: 94.1 percent / aq. potassium hydroxide / methanol / 16 h / Heating 6: 73.5 percent / N,N'-dicyclohexylcarbodiimide; N,N-dimethylaminopyridine / CH2Cl2 / 2 h View Scheme
参考文献
Katayama
Bioscience, biotechnology, and biochemistry, 2000 , vol. 64, # 4 p. 808 - 815