2-羟基-1,4-萘醌合成路线 （共 313 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=20°C; 10 h;
参考文献
Hagiwara, Hisahiro; Sato, Kouji; Nishino, Daisuke; Hoshi, Takashi; Suzuki, Toshio; Ando, Masayoshi
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 22 p. 2946 - 2957
反应条件
1: 53 percent / ceric ammonium nitrate / acetonitrile / 5 h / 0 °C
2: 95 percent / DBU / benzene / 5 h / 20 °C
View Scheme
参考文献
Hagiwara, Hisahiro; Sato, Kouji; Suzuki, Toshio; Ando, Masayoshi
Heterocycles, 1999 , vol. 51, # 3 p. 497 - 500
反应条件
1: 53 percent / ceric ammonium nitrate / acetonitrile / 5 h / 0 °C
2: 95 percent / DBU / benzene / 5 h / 20 °C
3: 90 percent / NaBH4 / methanol / 2 h / 20 °C
View Scheme
参考文献
Ferreira, V. F.; Pinto, A. V.; Pinto, M. C. F. R.; Cruz, M. C. da; Clarino, A.
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 1061 - 1070
反应条件
1: 9 percent / silver oxide / CHCl3
2: 1) dithionite, 2) NaOH / 1) ether
View Scheme
参考文献
Laaatsch
1983 , vol. NO. 11, p. 1886 - 1900
反应条件
1: 9 percent / silver oxide / CHCl3
2: 1) dithionite, 2) NaOH / 1) ether
View Scheme
参考文献
Laaatsch
1983 , vol. NO. 11, p. 1886 - 1900
反应条件
potassium hydroxide; potassium iodide
2.) HMPT, 45 deg C, 16 h; Yield given. Multistep reaction;
参考文献
Schaffner-Sabba, Karl; Schmidt-Ruppin, Karl H.; Wehrli, Walter; Schuerch, ALfred R.; Wasley, Jan W. F.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 990 - 994
反应条件
1: formaldehyd; 2-hydroxynaphthalene-1,4-dione in ethanol; water
Knoevenagel condensation; Heating;
2: styrene in ethanol; water
Diels-Alder reaction;
参考文献
Ferreira, Sabrina Baptista; Gonzaga, Daniel Tadeu Gomes; Decarvalhodasilva, Fernando; Delimaaraujo, Katia Gomes; Ferreira, Vitor Francisco
Synlett, 2011 , # 11 p. 1623 - 1625
反应条件
in ethanol; water
Reflux;
参考文献
Ferreira, Sabrina Baptista; Salomao, Kelly; De Carvalho Da Silva, Fernando; Pinto, Antonio Ventura; Kaiser, Carlos Roland; Pinto, Angelo C.; Ferreira, Vitor Francisco; De Castro, Solange L.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3071 - 3077
反应条件
acetic acid; platinum
T=50°C; Hydrogenation.Behandlung der vom Katalysator befreiten Reaktionsloesung mit K2Cr2O7 und wss.H2SO4.;
参考文献
Skita; Rohrmann
Chemische Berichte, 1930 , vol. 63, p. 1473,1484
反应条件
boron trifluoride diethyl etherate; acetic acid in water
T=100°C; 1.5 h;
参考文献
CREIGHTON UNIVERSITY
Patent: WO2006/107827 A1, 2006 ;
Location in patent: Page/Page column 27 ;
