1,2,3,4,6-alpha-D-葡萄糖五乙酸酯合成路线 （共 153 条）
反应条件
1: pyridine; hydrogen fluoride / -20 - 20 °C 2: methanol; sodium methylate / 20 °C 3: sodium hydroxide; Thermus nonproteolyticus HG102 E338A mutant; glycine / aq. buffer / 48 h / 45 °C / pH 8.8 / |Enzymatic reaction View Scheme
参考文献
European Journal of Organic Chemistry, , # 12 p. 2414 - 2419
反应条件
1: pyridine; hydrogen fluoride / -20 - 20 °C 2: methanol; sodium methylate / 20 °C 3: sodium hydroxide; Thermus nonproteolyticus HG102 E338A mutant; glycine / aq. buffer / 48 h / 45 °C / pH 8.8 / |Enzymatic reaction View Scheme
参考文献
European Journal of Organic Chemistry, , # 12 p. 2414 - 2419
反应条件
1: 99 percent / HBr; acetic acid / 1.5 h / 20 °C 2: Zn; NMI / ethyl acetate / 2 h / Heating View Scheme
参考文献
Cavallaro, Cullen L.; Schwartz, Jeffrey
Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 7055 - 7057
反应条件
1: 974.8 g / PBr3; H2O / 96 h / 20 °C 2: 57 percent / DBU / dimethylformamide / 1 h / -10 °C View Scheme
参考文献
Ichikawa, Yoshiyasu; Hirata, Keiko; Ohayashi, Masayoshi; Isobe, Minoru
Chemistry - A European Journal, 2004 , vol. 10, # 13 p. 3241 - 3251
反应条件
1: HBr; AcOH / 0.17 h / 0 °C 2: 65 percent / AgOTf / CH2Cl2 / 0.25 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 17 p. 6427 - 6433
反应条件
tin(IV) chloride T=0 - 20°C; 1.5 h;
参考文献
Asian Journal of Chemistry, , vol. 24, # 12 p. 5592 - 5596,5
Asian Journal of Chemistry, , vol. 24, # 12 p. 5592 - 5596
反应条件
pyridine; hydrogen fluoride T=20°C; 4 h; Sealed vial;
参考文献
Steinmann, Andreas; Thimm, Julian; Matwiejuk, Martin; Thiem, Joachim
Macromolecules, 2010 , vol. 43, # 8 p. 3606 - 3612
反应条件
1: BF3*Et2O / CH2Cl2 / 72 h / 20 °C 2: NaOMe / methanol / 2 h / 20 °C 3: 95 percent / Pd/C / methanol / 0.5 h / 20 °C View Scheme
参考文献
Westphal; Feier
Chemische Berichte, 1956 , vol. 89, p. 582,587
反应条件
1: TMsN3, SnCl4 2: H2 / Pd View Scheme
参考文献
Samarasimhareddy; Hemantha, Hosahalli P.; Sureshbabu, Vommina V.
Tetrahedron Letters, 2012 , vol. 53, # 24 p. 3104 - 3107
反应条件
1: boron trifluoride diethyl etherate / dichloromethane / 24 h / 20 °C / Inert atmosphere 2: methanol; water; triethylamine / 5 h / Inert atmosphere 3: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 2.5 h / 80 °C / Inert atmosphere View Scheme
参考文献
University of Iowa Research Foundation; Kraus, George A.; Maury, Wendy
Patent: US2013/252909 A1, 2013 ;
