1,2,3,4,6-alpha-D-葡萄糖五乙酸酯合成路线 （共 153 条）
反应条件
1: With boron trifluoride diethyl etherate T=20°C; 8 h; 2: With methanol 16 h; Reflux;
参考文献
ACADEMIA SINICA; LIANG, Chi-ming; HUNG, Shang-cheng; CHANG, Cheng-hsiu
Patent: WO2013/184564 A1, 2013 ;
Location in patent: Paragraph 00188; 00189 ;
反应条件
1: 81 percent / BF3*Et2O / CH2Cl2 / 16 h 2: 87 percent / MeONa / methanol / 1 h View Scheme
参考文献
Cai, Chao; Dickinson, Demetria M.; Li, Lingyun; Masuko, Sayaka; Suflita, Matt; Schultz, Victor; Nelson, Shawn D.; Bhaskar, Ujjwal; Liu, Jian; Linhardt, Robert J.
Organic Letters, 2014 , vol. 16, # 8 p. 2240 - 2243
反应条件
1: phosphorus; bromine; acetic acid 2: anhydrous xylene / 0.42 h / 130 - 140 °C / Microwave irradiation View Scheme
参考文献
Yadgire, Atul V.; Korpe, Gajanan V.; Deshmukh, Shirish P.
E-Journal of Chemistry, 2011 , vol. 8, # 4 p. 1614 - 1619
反应条件
1: pyridine; hydrogen fluoride / -20 - 20 °C 2: methanol; sodium methylate / 20 °C 3: sodium hydroxide; Thermus nonproteolyticus HG102 E338A mutant; glycine / aq. buffer / 48 h / 45 °C / pH 8.8 / |Enzymatic reaction View Scheme
参考文献
Wei, Jinhua; Lv, Xun; Lue, Yang; Yang, Gangzhu; Fu, Lifeng; Yang, Liu; Wang, Jianjun; Gao, Jianhui; Cheng, Shuihong; Duan, Qian; Jin, Cheng; Li, Xuebing
European Journal of Organic Chemistry, 2013 , # 12 p. 2414 - 2419
反应条件
1.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C / Inert atmosphere 2.1: methanol; sodium methylate / 20 °C 2.2: Amberlite.(R). IR-120 H+ ion exchange 3.1: sodium hydride / N,N-dimethyl-formamide / 2.5 h / 0 - 20 °C / Inert atmosphere 3.2: 12 h / 20 °C / Inert atmosphere 4.1: N-bromosuccinmide; water / acetone / 3 h / 20 °C 5.1: acetic anhydride; dimethyl sulfoxide / 12 h / 30 °C View Scheme
参考文献
Organic Letters, , vol. 13, # 14 p. 3628 - 3631
反应条件
tin(IV) chloride in dichloromethane T=20°C; 19 h; Inert atmosphere;
参考文献
Barry, Conor S.; Cocinero, Emilio J.; Carcabal, Pierre; Gamblin, David P.; Stanca-Kaposta, E. Cristina; Remmert, Sarah M.; Fernandez-Alonso, Maria C.; Rudic, Svemir; Simons, John P.; Davis, Benjamin G.
Journal of the American Chemical Society, 2013 , vol. 135, # 45 p. 16895 - 16903
反应条件
1: I2; HMDS / CH2Cl2 / 6 h / 20 °C 2: CH2Cl2 / 20 °C View Scheme
参考文献
Mukhopadhyay, Balaram; Kartha, K.P. Ravindranathan; Russell, David A.; Field, Robert A.
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7758 - 7760
反应条件
trimethylsilyl trifluoromethanesulfonate in dichloromethane 12 h;
参考文献
Wang, Haixing; Su, Fuqin; Zhou, Liang; Chen, Xiaoguang; Lei, Pingsheng
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 10 p. 2796 - 2800
反应条件
1: BF3*Et2O / CH2Cl2 / 72 h / 20 °C 2: NaOMe / methanol / 2 h / 20 °C View Scheme
参考文献
Jermyn
Australian Journal of Chemistry, 1955 , vol. 8, p. 403,407
Australian Journal of Chemistry, 1954 , vol. 7, p. 202,204
反应条件
1: zinc chloride 2: Raney nickel; aqueous ethanol View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 33, p. 109,116, 117
