lithium aluminium tetrahydride in diethyl ether 3 h; Heating;

1.1: 9-BBN / tetrahydrofuran / 48 h / 20 °C 1.2: 82 percent / NaOH; aq. H2O2 / tetrahydrofuran; ethanol / 1 h / Heating 2.1: 85 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 1 h / -78 - -10 °C 3.1: H2SO4 / diethyl ether; CHCl3 4.1: 9.56 g / p-TsOH / CHCl3 / 36 h / Heating 5.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 5.2: 51 percent / tetrahydrofuran; hexane / 13.5 h / -78 - 20 °C 6.1: 34 percent / LiAlH4 / diethyl ether / 3 h / Heating View Scheme

1.1: 9.56 g / p-TsOH / CHCl3 / 36 h / Heating 2.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: 51 percent / tetrahydrofuran; hexane / 13.5 h / -78 - 20 °C 3.1: 34 percent / LiAlH4 / diethyl ether / 3 h / Heating View Scheme

1.1: H2SO4 / diethyl ether; CHCl3 2.1: 9.56 g / p-TsOH / CHCl3 / 36 h / Heating 3.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 3.2: 51 percent / tetrahydrofuran; hexane / 13.5 h / -78 - 20 °C 4.1: 34 percent / LiAlH4 / diethyl ether / 3 h / Heating View Scheme

1.1: 85 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 1 h / -78 - -10 °C 2.1: H2SO4 / diethyl ether; CHCl3 3.1: 9.56 g / p-TsOH / CHCl3 / 36 h / Heating 4.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C 4.2: 51 percent / tetrahydrofuran; hexane / 13.5 h / -78 - 20 °C 5.1: 34 percent / LiAlH4 / diethyl ether / 3 h / Heating View Scheme

暂无反应条件数据