4-[(1E)-2-(3,5-二甲氧基苯基)乙烯基]-2-甲氧基苯酚合成路线 （共 27 条）
反应条件
1: Et3N / tetrahydrofuran / 1 h / 0 - 20 °C 2: 31 percent / Li, naphthalene / tetrahydrofuran / 2 h / 0 °C 3: 99 percent / dimethylsulfoxide / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 2 p. 417 - 421
反应条件
1: 31 percent / Li, naphthalene / tetrahydrofuran / 2 h / 0 °C 2: 99 percent / dimethylsulfoxide / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 62, # 2 p. 417 - 421
反应条件
1: 1.3 g / various solvent(s) / 20 h / 160 °C 2: 250 mg / Cu-bronz / quinoline / 7 h / 240 - 260 °C View Scheme
参考文献
Phytochemistry (Elsevier), , vol. 24, # 2 p. 321 - 324
反应条件
1: 1.3 g / various solvent(s) / 20 h / 160 °C 2: 250 mg / Cu-bronz / quinoline / 7 h / 240 - 260 °C View Scheme
参考文献
Phytochemistry (Elsevier), , vol. 24, # 2 p. 321 - 324
反应条件
1: HCl / methanol 2: diethyl ether View Scheme
参考文献
Phytochemistry (Elsevier), , vol. 15, p. 2006 - 2008
反应条件
piperidine T=160 - 170°C; 20 h; Yields of byproduct given;
参考文献
Prakash, Satya; Khan, Mushtaq A.; Khan, Khaliquz Zaman; Zaman, Asif
Phytochemistry (Elsevier), 1985 , vol. 24, # 3 p. 622 - 624
反应条件
1.1: 92 percent / triethylamine / dimethylformamide / 20 °C 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C 3.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C 4.1: 92 percent / potassium carbonate / acetone / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 1.2: tetrahydrofuran / 5 h / 20 °C 2.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C 3.1: 92 percent / potassium carbonate / acetone / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 1.2: tetrahydrofuran / 5 h / 20 °C 2.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C 3.1: 92 percent / potassium carbonate / acetone / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C 2: 92 percent / potassium carbonate / acetone / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
