1: 3-methyl-cyclohex-2-en-1-one With n-butyllithium; diisopropylamine in tetrahydrofuran
T=0°C;
2: With N,N,N',N',N'',N''-hexamethylphosphoric triamide in tetrahydrofuran
3: ethyl bromoacetate With water; ammonium chloride
more than 3 stages;
参考文献
SAN-EI GEN F.F.I., INC.
Patent: EP1787975 A1, 2007 ;
Location in patent: Page/Page column 10 ;