Ong, Helen H.; Caldwell, Steven R.; Profitt, James A.; Tegeler, John J.; Agnew, Marc N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2295 - 2303
1: SOCl2 / CH2Cl2 / 1 h / Heating
2: AlCl3 / CH2Cl2 / 1 h / Ambient temperature
3: NaBH4 / ethanol
4: 98 percent / BF3*OEt2 / acetic acid / 0.08 h / 120 °C
5: 74.7 percent / pyridine hydrochloride / 1 h / 180 °C
View Scheme
参考文献
Ong, Helen H.; Caldwell, Steven R.; Profitt, James A.; Tegeler, John J.; Agnew, Marc N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2295 - 2303
1: 99.5 percent / NaH / dimethylformamide / 0.5 h
2: SOCl2 / CH2Cl2 / 1 h / Heating
3: AlCl3 / CH2Cl2 / 1 h / Ambient temperature
4: NaBH4 / ethanol
5: 98 percent / BF3*OEt2 / acetic acid / 0.08 h / 120 °C
6: 74.7 percent / pyridine hydrochloride / 1 h / 180 °C
View Scheme
参考文献
Ong, Helen H.; Caldwell, Steven R.; Profitt, James A.; Tegeler, John J.; Agnew, Marc N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2295 - 2303
1: 98 percent / BF3*OEt2 / acetic acid / 0.08 h / 120 °C
2: 74.7 percent / pyridine hydrochloride / 1 h / 180 °C
View Scheme
参考文献
Ong, Helen H.; Caldwell, Steven R.; Profitt, James A.; Tegeler, John J.; Agnew, Marc N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2295 - 2303
1: NaBH4 / ethanol
2: 98 percent / BF3*OEt2 / acetic acid / 0.08 h / 120 °C
3: 74.7 percent / pyridine hydrochloride / 1 h / 180 °C
View Scheme
参考文献
Ong, Helen H.; Caldwell, Steven R.; Profitt, James A.; Tegeler, John J.; Agnew, Marc N.; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2295 - 2303
