2-甲基-4-(喹啉-2-基)3-丁炔-2-醇合成路线 （共 4 条）
反应条件
1: 61 percent / NaOH / toluene / 1 h / Heating 2: 61 percent / Cu2I2; piperidine / PdCl2(PPh3)2 / 72 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 61, # 38 p. 9042 - 9051
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
T=80°C; Sonogashira Cross-Coupling; 3 h; Inert atmosphere;
参考文献
Son, Myung-Hee; Kim, Ji Young; Lim, Eun Jeong; Baek, Du-Jong; Choi, Kihang; Lee, Jae Kyun; Pae, Ae Nim; Min, Sun-Joon; Cho, Yong Seo
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1472 - 1476
反应条件
1: 47 percent / POCl3 / 3 h / Heating
2: 92 percent / Et2NH; Cu2I2 / PdCl2(PPh3)2 / 0.5 h / 40 °C
View Scheme
参考文献
Rodriguez, J. Gonzalo; De Los Rios, Cristobal; Lafuente, Antonio
Tetrahedron, 2005 , vol. 61, # 38 p. 9042 - 9051
反应条件
sodium hydroxide in toluene
1 h; Heating;
参考文献
Rodriguez, J. Gonzalo; De Los Rios, Cristobal; Lafuente, Antonio
Tetrahedron, 2005 , vol. 61, # 38 p. 9042 - 9051
