反应条件
1: (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde With sodium periodate; sodium hydrogencarbonate in water
T=0 - 20°C; 2.66667 h; Inert atmosphere;
2: dimethyl methylphosphonoacetate With potassium carbonate in water
T=0 - 20°C; Horner-Wadsworth-Emmons olefination; 12.1667 h; Inert atmosphere;
参考文献
Spangenberg, Thomas; Schoenfelder, Angele; Breit, Bernhard; Mann, Andre
European Journal of Organic Chemistry, 2010 , # 31 p. 6005 - 6018