5-[(3-甲氧基-4-苯基甲氧基-苯基)甲基]嘧啶-2,4-二胺合成路线 （共 3 条）
反应条件
sodium methylate in ethanol
24 h; Heating;
参考文献
Hachtel; Haller; Seydel
Arzneimittel-Forschung/Drug Research, 1988 , vol. 38, # 12 p. 1778 - 1783
反应条件
1: Na-methylate / dimethylsulfoxide / 0.5 h / 65 - 75 °C
2: HCl cc. / propan-2-ol / 1 h / Heating
3: 67 percent / Na-methylate / ethanol / 24 h / Heating
View Scheme
参考文献
Hachtel; Haller; Seydel
Arzneimittel-Forschung/Drug Research, 1988 , vol. 38, # 12 p. 1778 - 1783
反应条件
1: HCl cc. / propan-2-ol / 1 h / Heating
2: 67 percent / Na-methylate / ethanol / 24 h / Heating
View Scheme
参考文献
Hachtel; Haller; Seydel
Arzneimittel-Forschung/Drug Research, 1988 , vol. 38, # 12 p. 1778 - 1783
