3,5-二-O-(叔丁基二甲基硅烷)-2-脱氧-D-核糖酸-1,4-内酯合成路线 （共 21 条）
反应条件
1: diethyl ether 2: 83.1 percent / trifluoroacetic acid / H2O / 2 h / Ambient temperature 3: 97.8 percent / imidazole / CH2Cl2 / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 15 p. 2762 - 2772
反应条件
1: 50 percent aq. CF3COOH / 2 h / 90 - 95 °C 2: pyridine / CH2Cl2 / 16 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 27, # 22 p. 2489 - 2490
反应条件
1: 67 percent / AcOH / tetrahydrofuran; H2O / 72 h / Ambient temperature 2: CF3COOH / H2O / 2 h / Ambient temperature 3: imidazole / dimethylformamide / 3 h / Ambient temperature View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 49, # 5 p. 1435 - 1440
反应条件
1: bromine / water / 120 h / 20 °C / Sealed tube 2: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 20 °C View Scheme
反应条件
1H-imidazole; air; water 1.) r.t., irradiation, 6 h, 2.) DMF; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Chemical Communications, , # 12 p. 1249 - 1250
反应条件
pyridine; 1H-imidazole; trifluoroacetic acid 1.) 90-95 deg C, 2 h, 2.) 23 deg C, 24 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 26, # 10.2 p. 1905 - 1908
Zhurnal Organicheskoi Khimii, , vol. 26, # 10 p. 2208 - 2213
反应条件
pyridine; trifluoroacetic acid 1.) 90-95 deg C, 2 h, 2.) CH2Cl2, 20 deg C, 16 h; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 26, # 10.2 p. 1905 - 1908
Zhurnal Organicheskoi Khimii, , vol. 26, # 10 p. 2208 - 2213
反应条件
1: 90.4 percent / DIBAL / toluene / 0.25 h / -78 °C 2: 62 percent / AcOH / tetrahydrofuran; H2O / 24 h / 60 - 70 °C View Scheme
参考文献
Yamamoto, Yoshihiro; Kirihata, Mitsunori; Ichimoto, Itsuo; Ueda, Hiroo
Agricultural and Biological Chemistry, 1985 , vol. 49, # 5 p. 1435 - 1440
反应条件
1: 90.4 percent / DIBAL / toluene / 0.25 h / -78 °C 2: 62 percent / AcOH / tetrahydrofuran; H2O / 24 h / 60 - 70 °C View Scheme
参考文献
Yamamoto, Yoshihiro; Kirihata, Mitsunori; Ichimoto, Itsuo; Ueda, Hiroo
Agricultural and Biological Chemistry, 1985 , vol. 49, # 5 p. 1435 - 1440
反应条件
1: 90.4 percent / DIBAL / toluene / 0.25 h / -78 °C 2: 62 percent / AcOH / tetrahydrofuran; H2O / 24 h / 60 - 70 °C View Scheme
参考文献
Yamamoto, Yoshihiro; Kirihata, Mitsunori; Ichimoto, Itsuo; Ueda, Hiroo
Agricultural and Biological Chemistry, 1985 , vol. 49, # 5 p. 1435 - 1440
