1: 69.1 percent / KOH / pyridine / 0.17 h / 100 °C 2: 70.8 percent / H2SO4 / acetic acid / 0.17 h / 100 °C 3: 85.4 percent / BBr3 / CH2Cl2 / 5 h / Ambient temperature View Scheme

1: 13.5 g / KOH / pyridine / 2 h / 40 °C 2: 13.0 g / conc.HCl / acetic acid / 2 h / Heating 3: 10 g / HI (d=1.7) / acetic anhydride / 6 h / 115 - 118 °C View Scheme

in pyridine T=100°C; 0.166667 h;

1: 13.5 g / KOH / pyridine / 2 h / 40 °C 2: 13.0 g / conc.HCl / acetic acid / 2 h / Heating 3: 10 g / HI (d=1.7) / acetic anhydride / 6 h / 115 - 118 °C 4: 250 mg / BF3*Et2O / 45 - 50 °C View Scheme

1: 69.1 percent / KOH / pyridine / 0.17 h / 100 °C 2: 70.8 percent / H2SO4 / acetic acid / 0.17 h / 100 °C 3: 85.4 percent / BBr3 / CH2Cl2 / 5 h / Ambient temperature 4: 73.1 percent / I2, TlOAc / CH2Cl2 / Ambient temperature 5: 71.3 percent / K2CO3 / Heating 6: 50 percent / Pd(PPh3)4, NaOH / dimethylformamide; H2O / 2 h / 80 °C 7: 30 percent / BBr3 / CHCl3 / Heating View Scheme

1: 69.1 percent / KOH / pyridine / 0.17 h / 100 °C 2: 70.8 percent / H2SO4 / acetic acid / 0.17 h / 100 °C View Scheme