4-甲基-2-氧代-2H-苯并吡喃-3-甲酸合成路线 （共 9 条）
反应条件
1: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / dichloromethane / 20 °C 2: tetrakis(triphenylphosphine) palladium(0) / deuterated toluene / 12 h / 70 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 22 p. 5157 - 5161
反应条件
lithium perchlorate
0.0208333 h; Irradiation;
参考文献
Bandgar; Uppalla; Sadavarte
Journal of Chemical Research - Part S, 2002 , # 1 p. 40 - 41
反应条件
sodium hydroxide in water
1 h; Reflux;
参考文献
Jana, Ranjan; Partridge, James J.; Tunge, Jon A.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 22 p. 5157 - 5161
反应条件
1: sodium ethylate; ethanol
2: pyridine; aq. NaOH solution / anschliessend Ansaeuern mit wss. Salzsaeure
View Scheme
参考文献
Schroeder; Link
Journal of the American Chemical Society, 1953 , vol. 75, p. 1886
反应条件
pyridine; sodium hydroxide
anschliessend Ansaeuern mit wss. Salzsaeure;
参考文献
Schroeder; Link
Journal of the American Chemical Society, 1953 , vol. 75, p. 1886
反应条件
1: 67 percent / diethyl ether / 1.) -70 grad C, 2 h, 2.) 0 grad C, 4 h, 3.) room temperature, 3 days
2: aq. NaOH
View Scheme
参考文献
Bonsignore, Leonardo; Loy, Guiseppe; Secci, Mario
Tetrahedron Letters, 1983 , vol. 24, # 45 p. 5013 - 5016
反应条件
1: 54 percent / diethyl ether / 1) 0 deg C, 8 h, 2) r.t., 3 d
2: 20percent aq. NaOH
View Scheme
参考文献
Bonsignore, Leonardo; Cabiddu, Salvatore; Loy, Giuseppe; Secci, Mario
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 463 - 464
参考文献
Bonsignore, Leonardo; Loy, Guiseppe; Secci, Mario
Tetrahedron Letters, 1983 , vol. 24, # 45 p. 5013 - 5016
参考文献
Bonsignore, Leonardo; Cabiddu, Salvatore; Loy, Giuseppe; Secci, Mario
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 463 - 464
