2-氨基-5-(4-硝基苯基)-1,3,4-噻二唑合成路线 （共 15 条）
反应条件
anhydrous iron chloride; sodium acetate in acetic acid T=20°C; 0.5 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5735 - 5738
反应条件
1: With trichlorophosphate 3 h; Reflux; 2: With water 4 h; Reflux; 3: With potassium hydroxide in water
参考文献
Asian Journal of Chemistry, , vol. 22, # 7 p. 5289 - 5296
反应条件
1: in ethanol Reflux; 2: With sulfuric acid in ethanol T=20°C;
参考文献
RSC Advances, , vol. 3, # 19 p. 6813 - 6816
参考文献
Agricultural and Biological Chemistry, , vol. 47, # 1 p. 103 - 105
反应条件
1: With anhydrous iron chloride in water T=90°C; 0.75 h; 2: With anhydrous trisodium citrate; citric acid in water Heating; 3: With ammonia in water
参考文献
Letters in Drug Design and Discovery, , vol. 9, # 7 p. 668 - 675
反应条件
anhydrous iron chloride; anhydrous trisodium citrate; citric acid in water T=80 - 90°C; 0.75 h;
参考文献
Archiv der Pharmazie, , vol. 346, # 11 p. 819 - 831
反应条件
1: sodium acetate / water / 20 °C 2: anhydrous iron chloride; sodium acetate / acetic acid / 0.5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 19 p. 5735 - 5738
反应条件
1: aqueous HCl 2: concentrated H2SO4 View Scheme
参考文献
Yakugaku Zasshi, , vol. 72, p. 1636
Chem.Abstr., , p. 9324
反应条件
1: hydrazine hydrate / ethanol / Reflux 2: hydrogenchloride / water / Heating 3: sulfuric acid View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4919 - 4923
反应条件
1: trichlorophosphate / water / 7 h / |Reflux 2: potassium hydroxide / water View Scheme
参考文献
Asian Journal of Chemistry, , vol. 25, # 8 p. 4203 - 4206
