(E)-1-甲基-1,2二苯基乙烯合成路线 （共 175 条）
反应条件
1: 1.) N-bromomagnesio-N-ethylaniline / 1.) ether, 15 deg C, 15 min; 2.) 1 h; ice, HCl 2: 43 percent / phosphorus oxychloride / benzene / 3 h View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 17, # 11 p. 2096 - 2100
Zhurnal Organicheskoi Khimii, , vol. 17, # 11 p. 2346 - 2350
反应条件
1: 95 percent / butyl-lithium, N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran / 1 h / -5 - 0 °C 2: 1.) lithium naphthalenide / 1.) THF, 0 deg C, 2.) THF, 1 h 3: 1.) lithium naphthalenide / 1.) THF, -78 deg C, 0.5 h, 2.) THF, -78 deg C -> room temperature 4: warm hydrogen bromide / acetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 183 - 194
反应条件
1: 1.) lithium naphthalenide / 1.) THF, 0 deg C, 2.) THF, 1 h 2: 1.) lithium naphthalenide / 1.) THF, -78 deg C, 0.5 h, 2.) THF, -78 deg C -> room temperature 3: warm hydrogen bromide / acetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 183 - 194
反应条件
1: 1.) lithium naphthalenide / 1.) THF, -78 deg C, 0.5 h, 2.) THF, -78 deg C -> room temperature 2: warm hydrogen bromide / acetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 183 - 194
反应条件
1: 1.) lithium naphthalenide / 1.) THF, -78 deg C, 0.5 h, 2.) THF, -78 deg C -> room temperature 2: warm hydrogen bromide / acetic acid View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 183 - 194
反应条件
1: 1) BuLi / 1) THF, -70 deg C, 15 min, 2) THF, -70 deg C, 15 min 2: 19 percent / 25percent hydrochloric acid / ethanol / 1 h / Heating View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 47, p. 457 - 463
反应条件
1.1: 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; copper(l) chloride; sodium t-butanolate / tetrahydrofuran / 0.08 h / 20 °C / |Inert atmosphere 1.2: 16 h / 20 °C / |Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); sodium hydroxide / tetrahydrofuran; water / 16 h / 70 °C / |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 37 p. 15165 - 15168
反应条件
cesium fluoride in tetrahydrofuran Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 60, p. 1831 - 1838
反应条件
in tetrahydrofuran T=60°C; 12 h; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 39, # 51 p. 9331 - 9334
反应条件
24 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 108, # 6 p. 1322 - 1323
