(E)-1-甲基-1,2二苯基乙烯合成路线 （共 175 条）
反应条件
1: (1-phenylethyl)triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.5 h; 2: benzaldehyde in tetrahydrofuran; hexane 2 h;
参考文献
Journal of Organic Chemistry, , vol. 76, # 17 p. 7204 - 7215
反应条件
1: palladium diacetate; triphenylphosphine; caesium carbonate / tetrahydrofuran / 5 h / 40 °C / |Inert atmosphere 2: NiCl2(PPh3)2 / tetrahydrofuran / 12 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 13 p. 2175 - 2185
反应条件
1: acetic acid; lithium chloride / 24 h / 20 °C 2: palladium diacetate; triphenylphosphine; caesium carbonate / tetrahydrofuran / 5 h / 40 °C / |Inert atmosphere 3: NiCl2(PPh3)2 / tetrahydrofuran / 12 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 13 p. 2175 - 2185
反应条件
copper acetylacetonate; triphenylphosphine; lithium tert-butylate in toluene T=90°C; Wittig Olefination; 10 h; Schlenk techniqueInert atmosphere; Overall yield = 52 percent; Overall yield = 50.5 mg;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 11-12 p. 2145 - 2150
反应条件
1: 82 percent / Cl2Pd(DPEphos) / tetrahydrofuran / 6 h / 23 °C 2: 91 percent / Pd(tBu3P)2 / tetrahydrofuran / 3 h / 50 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 687, # 2 p. 518 - 524
反应条件
1.1: NaI; Et3N / acetonitrile / 60 °C 2.1: SO2Cl2 / CH2Cl2 / 1 h / -40 °C 2.2: 4.25 g / CH2Cl2 / -40 - 20 °C 3.1: NaBH4 / methanol / 4 h View Scheme
参考文献
Tetrahedron, , vol. 59, # 32 p. 6057 - 6066
反应条件
1.1: SO2Cl2 / CH2Cl2 / 1 h / -40 °C 1.2: 4.25 g / CH2Cl2 / -40 - 20 °C 2.1: NaBH4 / methanol / 4 h View Scheme
参考文献
Tetrahedron, , vol. 59, # 32 p. 6057 - 6066
反应条件
1: 65 percent / (Ph3P)4Pd, CuI / dimethylformamide / 40 h / Ambient temperature 2: 63 percent / (PH3P)2NiCl2 / tetrahydrofuran / 48 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 4 p. 417 - 419
反应条件
[Al2O3]0.5[ZrO2]0.5 composite T=280°C; Neat (no solvent)Flow conditions; optical yield given as percent de;
参考文献
Applied Catalysis A: General, , vol. 404, # 1-2 p. 141 - 148
反应条件
sodium tetrahydroborate in methanol 4 h; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 59, # 32 p. 6057 - 6066
