(S)-n-乙酰基-2-(2-噻吩)丙氨酸合成路线 （共 4 条）
反应条件
hydrogen; lt;Rh+(COD)(S,S)-DIOPgt;+ClO4- in ethanol
T=50°C; P=760 Torr; Title compound not separated from byproducts;
参考文献
Cativiela, Carlos; Mayoral, Jose A.; Melendez, Enrique; Oro, Luis A.; Pinillos, Maria T.; Uson, Rafael
Journal of Organic Chemistry, 1984 , vol. 49, # 13 p. 2502 - 2504
反应条件
hydrogen; Rh(I)-chiral hydroxyl bisphospholane in methanol
T=20°C; Hydrogenation; P=2280 Torr; 12 h;
参考文献
Li, Wenge; Zhang, Zhaoguo; Xiao, Dengming; Zhang, Xumu
Tetrahedron Letters, 1999 , vol. 40, # 37 p. 6701 - 6704
反应条件
2: H2O
3: H2, (-)-(R)-PROPRAPHOS rhodium complex / methanol / 25 °C / 760 Torr
View Scheme
参考文献
Doebler, Christian; Kreuzfeld, H.-J.; Krause, H. W.; Michalik, M.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 8 p. 1833 - 1842
反应条件
1: H2O
2: H2, (-)-(R)-PROPRAPHOS rhodium complex / methanol / 25 °C / 760 Torr
View Scheme
参考文献
Doebler, Christian; Kreuzfeld, H.-J.; Krause, H. W.; Michalik, M.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 8 p. 1833 - 1842
