4 -甲氧基二苯基甲烷合成路线 （共 196 条）
反应条件
potassium carbonate in acetone
T=0 - 20°C; Inert atmosphere;
参考文献
Li, Hui-Jing; Guillot, Regis; Gandon, Vincent
Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8435 - 8449
反应条件
Pd(P(o-Tol)3)2; CyPF-tBu in diethyl ether; toluene
T=20°C; Kumada coupling; 4 h;
参考文献
Limmert, Michael E.; Roy, Amy H.; Hartwig, John F.
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9364 - 9370
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran
2: With copper(l) chloride; triethyl phosphite in tetrahydrofuran; ethylene glycol dimethyl ether
T=-15°C; 0.166667 h;
3: BnOP(O)(OEt)2 With tetra-(n-butyl)ammonium iodide in tetrahydrofuran; ethylene glycol dimethyl ether
T=60°C; 1.5 h;
参考文献
Kofink, Christiane C.; Knochel, Paul
Organic Letters, 2006 , vol. 8, # 18 p. 4121 - 4124
反应条件
potassium fluoride; (R)-N-(2-methoxybenzylidene)-1-phenylethanamine; palladium diacetate in tetrahydrofuran
T=0 - 35°C; Suzuki-Miyaura coupling reaction; 2.5 h; Inert atmosphere;
参考文献
Srimani, Dipankar; Sarkar, Amitabha
Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6304 - 6307
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; potassium carbonate in tetrahydrofuran; water
T=80°C; Suzuki-Miyaura Coupling; 48 h; Inert atmosphereSealed tube;
参考文献
St. Denis, Jeffrey D.; Scully, Conor C. G.; Lee, C. Frank; Yudin, Andrei K.
Organic Letters, 2014 , vol. 16, # 5 p. 1338 - 1341
反应条件
HPF6
T=25°C; 0.5 h; Product distribution;
参考文献
Olah, George A.; Olah, Judith A.; Ohyama, Toshiyuki
Journal of the American Chemical Society, 1984 , vol. 106, # 18 p. 5284 - 5290
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; potassium phosphate in tetrahydrofuran
T=60°C; Suzuki-Miyaura reaction; 16 h;
参考文献
Flaherty, Alice; Trunkfield, Amy; Barton, William
Organic Letters, 2005 , vol. 7, # 22 p. 4975 - 4978
反应条件
iron (III) acetylacetonate; ethylene dibromide in tetrahydrofuran
T=20°C; 3 h; Inert atmosphere;
参考文献
Cahiez, Gerard; Foulgoc, Laura; Moyeux, Alban
Angewandte Chemie, International Edition, 2009 , vol. 48, # 16 p. 2969 - 2972
反应条件
potassium phosphate; palladium diacetate; tri-cyclo-hexyl-phosphine in water
T=80°C; Suzuki carbonylation; P=7500.75 Torr; 20 h; Inert atmosphere;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Tetrahedron Letters, 2010 , vol. 51, # 47 p. 6146 - 6149
反应条件
C4H6Cl2N2Ni; C33H27NP2 in tetrahydrofuran
T=20°C; Kumada-Corriu reaction; 8 h; Inert atmosphere;
参考文献
Ghosh, Raju; Sarkar, Amitabha
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8283 - 8286
