4 -甲氧基二苯基甲烷合成路线 （共 196 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in N,N-dimethyl-formamide
T=90°C; 2 h; Schlenk techniqueInert atmosphere; Reagent/catalyst;
参考文献
Rao, Maddali L. N.; Dhanorkar, Ritesh J.
RSC Advances, 2014 , vol. 4, # 25 p. 13134 - 13144
反应条件
1: benzyl alcohol With n-butyllithium; chloro-diphenylphosphine in tetrahydrofuran
2: With methyl iodide in tetrahydrofuran
T=20°C; 1 h;
3: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=20°C; 1 h;
参考文献
Shintou, Taichi; Kikuchi, Wataru; Mukaiyama, Teruaki
Chemistry Letters, 2003 , vol. 32, # 8 p. 676 - 677
反应条件
1: (4-methoxyphenyl)methanol With n-butyllithium; chloro-diphenylphosphine in tetrahydrofuran
2: With methyl iodide in tetrahydrofuran
T=20°C; 1 h;
3: phenyl-magnesium chloride in tetrahydrofuran
T=20°C; 1 h;
参考文献
Shintou, Taichi; Kikuchi, Wataru; Mukaiyama, Teruaki
Chemistry Letters, 2003 , vol. 32, # 8 p. 676 - 677
反应条件
1: (4-methoxyphenyl)methanol With n-butyllithium; chloro-diphenylphosphine in tetrahydrofuran
2: With methyl iodide in tetrahydrofuran
T=20°C; 1 h;
3: Bromure de phenyl magnesium in tetrahydrofuran
T=20°C; 1 h;
参考文献
Shintou, Taichi; Kikuchi, Wataru; Mukaiyama, Teruaki
Chemistry Letters, 2003 , vol. 32, # 8 p. 676 - 677
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; anhydrous copper acetate in tetrahydrofuran
T=80°C; 8 h;
参考文献
Nakao, Yoshiaki; Ebata, Shiro; Chen, Jinshui; Imanaka, Hidekazu; Hiyama, Tamejiro
Chemistry Letters, 2007 , vol. 36, # 5 p. 606 - 607
反应条件
1: Et3N / 2-methyl-butan-2-ol / 12 h / 20 °C
2: 94 percent / K2CO3; DPEphos / [Pd(η3-C3H5)Cl]2 / 2-methyl-butan-2-ol / 3 h / 80 °C
View Scheme
参考文献
Kuwano, Ryoichi; Yokogi, Masashi
Chemical Communications, 2005 , # 47 p. 5899 - 5901
反应条件
bis(η3-allyl-μ-chloropalladium(II)); 1,5-bis-(diphenylphosphino)-pentane in N,N-dimethyl-formamide
T=80°C; Kosugi-Migita-Stille coupling reaction; 72 h;
参考文献
Ohsumi, Masato; Kuwano, Ryoichi
Chemistry Letters, 2008 , vol. 37, # 7 p. 796 - 797
反应条件
C4H6Cl2N2Ni; C33H27NP2 in tetrahydrofuran
T=20°C; Kumada-Corriu reaction; 8 h; Inert atmosphere;
参考文献
Ghosh, Raju; Sarkar, Amitabha
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8283 - 8286
反应条件
tetrabutyl ammonium fluoride; palladium in tetrahydrofuran
T=70°C; Hiyama coupling; 2 h; Inert atmosphere;
参考文献
Srimani, Dipankar; Bej, Ansuman; Sarkar, Amitabha
Journal of Organic Chemistry, 2010 , vol. 75, # 12 p. 4296 - 4299
反应条件
palladium diacetate; tris(4-methylphenyl)-phosphine in toluene
T=25°C; 2 h; Inert atmosphere;
参考文献
Chen, Chi-Ren; Zhou, Shuangliu; Biradar, Deepak Baburao; Gau, Han-Mou
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 10 p. 1718 - 1727
