5-[(2-氯苯基)甲基]-5,6,7,7a-四氢噻吩并[3,2-c]吡啶-2(4H)-酮合成路线 （共 2 条）
反应条件
n-butyllithium; dihydrogen peroxide; oxalic acid in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane; acetone
参考文献
Sanofi
Patent: US4515951 A1, 1985 ;
反应条件
glucose-6-phosphate dehydrogenase; G6P; cytochrome P450 2C19; NADP; magnesium chloride in aq. phosphate buffer
T=37°C; pH=7.4; Enzymatic reaction; Reagent/catalyst;
参考文献
Kim, Min-Jung; Jeong, Eun Sook; Park, Jung-Soon; Lee, Su-Jun; Ghim, Jong Lyul; Choi, Chang-Soo; Shin, Jae-Gook; Kim, Dong-Hyun
Drug Metabolism and Disposition, 2014 , vol. 42, # 1 p. 141 - 152
