bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=20°C;

lithium diisopropyl amide in tetrahydrofuran 1.) -78 deg C, 3 h, 2.) -30 deg C to r.t., 12 h;

lithium diisopropyl amide 1.) Et2O, THF, -78 deg C, 30 min, 2.) Et2O, THF, from -78 deg C to RT, 30 min; Yield given. Multistep reaction;

1: With n-butyllithium in tetrahydrofuran; hexane T=-70 - -40°C; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; hexane; water T=0°C; pH=3;

n-butyllithium; N,N,N',N,-tetramethylethylenediamine 1.) Et2O, hexane, -78 deg C, 30 min, 2.) Et2O, hexane, from -78 deg C, 1 h to RT, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;