4-苯基吡啶-2,6-二羧酸合成路线 （共 11 条）
反应条件
in diphenylether T=220°C;
参考文献
Weller, Dwight D.; Luellen, Glenn R.; Weller, Doreen L.
Journal of Organic Chemistry, 1982 , vol. 47, # 24 p. 4803 - 4806
反应条件
potassium permanganate in acetone
T=25°C; 96 h;
参考文献
Weller, Dwight D.; Luellen, Glenn R.; Weller, Doreen L.
Journal of Organic Chemistry, 1982 , vol. 47, # 24 p. 4803 - 4806
反应条件
potassium permanganate in water
18 h; Heating;
参考文献
Van Staveren,C.; Aarts,V.; Grootenhuis,P.
Journal of the American Chemical Society, 1988 , vol. 110, p. 8134
反应条件
water; potassium carbonate in methanol
T=20°C; 18 h;
参考文献
Tse, Man Kin; Bhor, Santosh; Klawonn, Markus; Anilkumar, Gopinathan; Jiao, Haijun; Doebler, Christian; Spannenberg, Anke; Magerlein, Wolfgang; Hugl, Herbert; Beller, Matthias
Chemistry - A European Journal, 2006 , vol. 12, # 7 p. 1855 - 1874
反应条件
hydrogenchloride; potassium permanganate in butan-1-ol
参考文献
Baxter Travenol Laboratories, Inc.
Patent: US4761481 A1, 1988 ;
反应条件
1: 52 percent / P(o-Tolyl)3; CsF / Pd(OAc)2 / 1,2-dimethoxy-ethane / 18 h / 100 °C
2: 86 percent / H2O; K2CO3 / methanol / 18 h / 20 °C
View Scheme
参考文献
Tse, Man Kin; Bhor, Santosh; Klawonn, Markus; Anilkumar, Gopinathan; Jiao, Haijun; Doebler, Christian; Spannenberg, Anke; Magerlein, Wolfgang; Hugl, Herbert; Beller, Matthias
Chemistry - A European Journal, 2006 , vol. 12, # 7 p. 1855 - 1874
反应条件
1: 52 percent / P(o-Tolyl)3; CsF / Pd(OAc)2 / 1,2-dimethoxy-ethane / 18 h / 100 °C
2: 86 percent / H2O; K2CO3 / methanol / 18 h / 20 °C
View Scheme
参考文献
Tse, Man Kin; Bhor, Santosh; Klawonn, Markus; Anilkumar, Gopinathan; Jiao, Haijun; Doebler, Christian; Spannenberg, Anke; Magerlein, Wolfgang; Hugl, Herbert; Beller, Matthias
Chemistry - A European Journal, 2006 , vol. 12, # 7 p. 1855 - 1874
反应条件
1: SOCl2 / dimethylformamide / 48 h / Heating
2: 52 percent / P(o-Tolyl)3; CsF / Pd(OAc)2 / 1,2-dimethoxy-ethane / 18 h / 100 °C
3: 86 percent / H2O; K2CO3 / methanol / 18 h / 20 °C
View Scheme
参考文献
Tse, Man Kin; Bhor, Santosh; Klawonn, Markus; Anilkumar, Gopinathan; Jiao, Haijun; Doebler, Christian; Spannenberg, Anke; Magerlein, Wolfgang; Hugl, Herbert; Beller, Matthias
Chemistry - A European Journal, 2006 , vol. 12, # 7 p. 1855 - 1874
反应条件
lithium hydroxide hydrate in tetrahydrofuran
T=20°C;
参考文献
Ghoshal, Atanu; Sarkar, Asit R.; Manickam, Govindaswamy; Kumaran, R. Senthil; Jayashankaran
Synlett, 2010 , # 10 p. 1459 - 1462
反应条件
1: 72 percent / hydroxylamine hydrochloride / butan-1-ol / 6 h / Heating
2: 87 percent / KMnO4 / acetone / 96 h / 25 °C
View Scheme
参考文献
Weller, Dwight D.; Luellen, Glenn R.; Weller, Doreen L.
Journal of Organic Chemistry, 1982 , vol. 47, # 24 p. 4803 - 4806
