3,5-二甲基-4-(2-甲氧基乙基)-1H-吡唑合成路线 (共 2 条)
反应条件
1: With trifluoroacetic acid in methanol; dichloromethane
T=75°C; 16 h;
2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
MALLINCKRODT INC.
Patent: WO2008/61792 A2, 2008 ;
Location in patent: Page/Page column 14-15; 2/13 ;
反应条件
hydrazine hydrate
12 h; Ambient temperature;
参考文献
Zefirov, Nikolai S.; Kozhushkov, Sergei I.; Kuznetsova, Tamara S.
Tetrahedron, 1982 , vol. 38, # 11 p. 1693 - 1697