Pillay, Adushan; Rousseau, Amanda L.; Fernandes, Manuel A.; De Koning, Charles B.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 38 p. 7809 - 7819
lithium aluminium tetrahydride in tetrahydrofuran
T=20°C;
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
1: 92 percent / t-BuOK / 2-methyl-propan-2-ol / 0.67 h / Heating
2: 81 percent / Ac2O / 0.75 h / Heating
3: 84 percent / aq. NaOH / ethanol / 0.17 h / 20 °C
4: 93 percent / K2CO3 / acetone / 16 h / Heating
5: 160 °C
6: 0.74 g / K2CO3 / acetone / 16 h / Heating
7: 87 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
1: neat (no solvent) / 18 h / |Inert atmosphere; |Reflux
2: potassium carbonate; dimethyl sulfate / acetone / 12 h / |Reflux
3: lithium aluminium tetrahydride / diethyl ether / 2 h / 0 - 40 °C / |Inert atmosphere
View Scheme
参考文献
Pillay, Adushan; Rousseau, Amanda L.; Fernandes, Manuel A.; De Koning, Charles B.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 38 p. 7809 - 7819
Pillay, Adushan; Rousseau, Amanda L.; Fernandes, Manuel A.; De Koning, Charles B.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 38 p. 7809 - 7819
1: 81 percent / Ac2O / 0.75 h / Heating
2: 84 percent / aq. NaOH / ethanol / 0.17 h / 20 °C
3: 93 percent / K2CO3 / acetone / 16 h / Heating
4: 160 °C
5: 0.74 g / K2CO3 / acetone / 16 h / Heating
6: 87 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
1: 93 percent / K2CO3 / acetone / 16 h / Heating
2: 160 °C
3: 0.74 g / K2CO3 / acetone / 16 h / Heating
4: 87 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
1: 160 °C
2: 0.74 g / K2CO3 / acetone / 16 h / Heating
3: 87 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
dimethyl sulfoxide; triethylamine; trifluoroacetic anhydride in dichloromethane
T=-60 - 20°C;
参考文献
De Koning, Charles B.; Manzini, Sunnyboy S.; Michael, Joseph P.; Mmutlane, Edwin M.; Tshabidi, Tefo R.; Van Otterlo, Willem A.L.
Tetrahedron, 2005 , vol. 61, # 3 p. 555 - 564
