4-氯-2-(3-吡啶)-6-甲基嘧啶合成路线 （共 3 条）
反应条件
1: With sodium methylate in ethanol
T=90°C; 4 h;
2: With trichlorophosphate in ethanol
T=120°C; 3 h;
3: With sodium hydroxide in ethanol; water
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/79791 A1, 2006 ;
Location in patent: Page/Page column 43 ;
WO 2006/079791 A1
参考文献
Brown; Cowden
Australian Journal of Chemistry, 1982 , vol. 35, # 6 p. 1203 - 1207
反应条件
1: 32 percent / sodium ethoxide / ethanol / 3 h / Heating
2: 42 percent / phosphoryl chloride
View Scheme
参考文献
Brown; Cowden
Australian Journal of Chemistry, 1982 , vol. 35, # 6 p. 1203 - 1207
