4-(3-甲氧基苯基)噻唑-2-胺合成路线 （共 6 条）
参考文献
VERTEX PHARMACEUTICALS INCORPORATED; CLEVELAND, Thomas; MAKINGS, Lewis R.; HAMILTON, Matthew; GROOTENHUIS, Peter D.J.
Patent: WO2005/26137 A2, 2005 ;
Location in patent: Page/Page column 247-248 ;
WO 2005/026137 A2
反应条件
aluminum oxide; ammonium acetate; silica gel in benzene T=90°C; 16 h;
参考文献
Jung, Kwan-Young; Kim, Soo-Kyung; Gao, Zhan-Guo; Gross, Ariel S.; Melman, Neli; Jacobson, Kenneth A.; Kim, Yong-Chul
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 3 p. 613 - 623
参考文献
Bhargava; Lakhan; Tripathi
Journal of the Indian Chemical Society, 1982 , vol. 59, # 6 p. 773 - 775
反应条件
1: polymer-supported pyridinium bromide perbromide / toluene / 10 °C 2: polymer-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene / acetonitrile / 0.25 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 17 p. 2425 - 2428
反应条件
Yield given. Multistep reaction;
参考文献
Chemical Communications, , # 18 p. 2019 - 2020
反应条件
triethylamine in tetrahydrofuran
3 h; Ambient temperature;
参考文献
Cousse; Mouzin; Bonnaud; Tarayre; Couzinier
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 9 p. 1391 - 1393
