反应条件
1: 3.1 g / thionyl chloride / diethyl ether / 2 h / Heating 2: 4.2 g / n-butyl-lithium / hexane; tetrahydrofuran / 1.) -23 deg C, 1.5 h, 2.) 0 deg C, 14 h 3: 3.6 g / mercuric oxide, mercuric chloride / acetonitrile / 6 h / Heating 4: 1.) Raney nickel, 2.) hydrogen / 2.) palladium on charcoal / 1.) ethanol, reflux, 15 - 20 min, 2.) methanol, 5: 2.5 g / triethylamine / CH2Cl2 / 0.17 h / 0 - 10 °C 6: 1.12 g / aq. hydrochloric acid / tetrahydrofuran / 0.67 h / 18 °C 7: 1.83 g / sodium borohydride / methanol / 0.17 h / Ambient temperature 8: sodium hydroxide / methanol; H2O / 1 h / 70 °C View Scheme
参考文献
Battersby; Chrystal; Staunton
Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 1, p. 31 - 42
